8 Best Soothing Moisturizers to Use with Differin [2020]
Our Black Friday/Cyber Monday offer ends in Use Coupon: ZLBLACK25 for 25% OFF

8 Best Soothing Moisturizers to Use with Differin

If you buy through external links, we may earn a small affiliate commission. Learn more.

best moisturizer differin
In a hurry? Here are our top picks:
BEST FOR SENSITIVE AND ACNE-PRONE SKIN ZELEN Life Moisturizer

 

The best moisturizers to use with Differin are those that allow the product to work effectively in your skin while restoring and maintaining a healthy skin barrier.

So you can fight acne while keeping your skin supple, healthy, and glowing, not dry and flaky.

In this article, we have identified our top 8 moisturizers that complement your Differin regimen by helping to soothe your skin after it is applied.

Keep reading to find a comprehensive review of each moisturizer, where we highlight their best features, strengths, and the things to look out for. We also share with you our selection process and answer the most frequently asked questions when using a moisturizer with Differin.

Let’s start things off with the key things to consider before purchasing your next moisturizer.

Quick summary

bb2-table__imageZELEN Life Moisturizer
  • Organic, non-comedogenic formula boosts hydration
  • Absorbs fast and soothing, ideal for Differin users
  • Packed with vitamins, essential fatty acids and antioxidants
Check It Out
bb2-table__imageDDF Ultra-Lite Oil-Free Moisturizing Dew
  • Lightweight texture
  • Replenishes and strengthens moisture
  • Fast absorption
Check on Amazon
bb2-table__imageELEMIS S.O.S Emergency Cream Intensive Moisturizer
  • Soothes blemish prone skin
  • Hydrates with intense action
  • Anti-inflammatory
Check on Amazon
bb2-table__imageMurad Hydration Hydro-Dynamic Ultimate Moisture
  • Superior hydration
  • Anti-aging benefits
  • Locks in moisture, non-greasy
Check on Amazon
bb2-table__imageMario Badescu Aloe Moisturizer SPF 15
  • Oil free with sun protection
  • Suitable for sensitive skin
  • Aloe-based formula
Check on Amazon
bb2-table__imageELEMIS Superfood Cica Calm Hydration Juice
  • Gel-based prebiotic formula
  • Hydrates and soothes skin
  • Contains biotransformed Cica, skin calming
Check on Amazon
bb2-table__imageJack Black Dry Erase Ultra-Calming Face Cream
  • Moisturizes and calms dry skin
  • Contains botanical extracts
  • Reduces redness, can be used overnight
Check on Amazon
bb2-table__imageL’Occitane Ultra-Rich Comforting Cream
  • Strong occlusive properties lock moisture
  • Loaded with vitamin E
  • 25% Shea butter, extra nourishing
Check on Amazon

Before you buy: 5 Things to consider when choosing a moisturizer to use with Differin

Choosing the best moisturizer to use with Differin is of paramount importance, and can make or break how you perform, as well as how you do with the medication.

Differin is an over-the-counter topical medication that belongs to the retinoid class of medications and comes in different strengths – an over-the-counter 0.1% and a prescription 0.3%.(1)

If used without a moisturizer, it can simply become too harsh, drying, and irritating to the skin. You may even start to peel like a snake and develop a rash or contact dermatitis.(2) Such as experience often turns someone off from ever trying Differin again.

However, if used with a good, soothing emollient or moisturizer, it can leave your skin glowing, hydrated, and with a strong skin barrier, yet devoid of acne or pimples, which is what we all desire to look like.

1. What is your skin type?

Know your skin type and which moisturizer might work best with it. If you have oily skin, choose a lighter formula. Similarly, if you have drier skin, you will need a more occlusive intense hydration.

If you have acne-prone skin, look for key words such as “oil-free” and “non-comedogenic,” meaning it does not cause zits or pimples.

If you like to wear makeup underneath or on top of your skincare routine, you can also find products that can be used with makeup and do not smear or interfere with their effect or with your makeover.

2. Address pre-existing and unresolved skin conditions

It is important to address any pre-existing or unresolved skin problems such as acne, seborrheic dermatitis, rosacea, tinea, or psoriasis.

While skincare products are there to help boost your overall skincare goals, they are not medications and cannot be used to treat/fight a pestering skin condition that you haven’t been able to get under control.

Make sure you ask all of your dermatologic and medical questions to your dermatologist to maximize control over these issues so that your skin can look its best when combining it with your skincare routine.

3. Know the ingredients

It is especially important to know the ingredients within your skincare products. Are you trying to go all-organic and all-natural?

You can find many of these ingredients in many skincare products if you look carefully. If you are against animal testing, look for a sign that says “cruelty-free,” meaning the product is not tested on animals.

If you are allergic to commonly found substances in skincare products such as propylene glycol, lanolin, or parabens, it is also important to know to search for these items beforehand.

Becoming familiar with the list of ingredients in your products ensures that you know what you are putting on your skin, and if you have an allergy, you will know better what to avoid or what the possible culprit may be.

4. Define your goals on what you want your moisturizer to do

What are your skincare goals? If your goal is to stay looking young and supple, you may find skincare products with these same goals.

If you are looking for something to hydrate your skin during typical drying times, such as a trip to the desert, a flight, or during wintertime, look for a product that provides intense hydration or a soothing emollient.

Similarly, if you want sun protection when going outside, look for a product that states it provides sun protection factor or SPF.

If you are looking for tint in addition to a moisturizer, you may find this on the bottle as “tinted” – when testing the product. The substance will come out with a flesh-colored or nude tint instead of white or clear.

5. What other things can your moisturizer do apart from moisturizing?

In addition to moisturizing, what are your other criteria for choosing a moisturizer? What else would you like it to do?

If you would like to use it morning and evening to be combined with makeup, topical therapies such as Differin, or other additions, look for a versatile product that can be used twice daily. If you would like something to diminish your redness, search for a product that targets this specific problem.

If you don’t like appearing with a shiny complexion, there are also mattifying products that can camouflage shine.

The 8 best moisturizers to use with Differin in 2020

1. ZELEN Life Moisturizer

moisturizer zelen life

Best features:

  • Handmade with vitamin C, vitamin E, antioxidants, calendula, clary sage, and organic oil-based jojoba
  • Light, non-greasy formula that absorbs quickly and provides hydration
  • Non-comedogenic, occlusive moisturizer that can be used in all skin types, genders, and ages

The best moisturizer to use with Differin for:

Men and women who desire a natural mattifying look.

Overview:

This moisturizer helps to facilitate skin hydration into your overall skincare routine on a daily basis. The moisturizing day cream is lightweight, not greasy, and formulated with a natural formula packed with organic ingredients.

Also, it does not contain fragrances, sulfates, synthetic dyes, paragons, or petrochemicals. Its all-natural ingredients include calendula, clary sage, and jojoba oil.

It gently moisturizes the skin, providing hydration without clogging pores. It is also suitable for men and all skin types, including those with sensitive skin. It helps to protect against environmental elements providing an added barrier of protection.

In addition, it is hypoallergenic and contains essential oils, fatty acids, and antioxidants. This product is cruelty-free and is never tested on animals.

Most of the product’s benefits come from clary sage, calendula, and jojoba oil.

Jojoba oil is commonly found in skincare products due to its benefits, which include: anti-aging, healing, balancing properties, and sebum regulation.(3)

Calendula is a natural oil extracted from marigold plants that provide many benefits, including daily moisture, healing skin without inducing redness, and providing a natural antiseptic.(4)

Clary sage is an herb native to the Mediterranean, which is often used in aromatherapy and has many beneficial advantages, including skin tightening to provide a youthful glow, antibacterial properties to prevent bacterial growth, and an anti-inflammatory effect to prevent irritation.(5)

Main ingredients:

Sunflower seed oil, Jojoba oil, Rose Geranium flower water, Clary sage, Calendula flower extract.

The good:

  • Does not clog pores, yet moisturizes and hydrates
  • Acts as a protective barrier from daily elements
  • Hypoallergenic
  • Contains essential fatty acids, vitamins, and antioxidants
  • Cruelty-free: the product is not tested on animals
  • Has a calming, soothing effect while also leaving it revitalized and refreshed

Things to think about:

  • It does not contain sunscreen or SPF, so if used in the daytime or sun exposure, you will need an additional sunscreen with the moisturizer

Bottom line:

The ZELEN Life Moisturizer can be used in any type of skin, whether its acne-prone, oily, dry, or combination skin. In addition to being non-comedogenic, it is also silicone-, alcohol-, fragrance-, and cruelty-free. It is an excellent addition to your daily routine if desiring a natural, illuminating yet mattifying appearance with handmade, organic ingredients, vitamins, and antioxidants.

2. DDF Ultra-Lite Oil-Free Moisturizing Dew

Best features:

  • Oil-free, fragrance-free, and dye-free moisturizer
  • Ultra-light moisturizer that does not clog pores
  • Absorbs quickly and replenishes moisture

The best moisturizer to use with Differin for:

Those who are seeking a light moisturizer that does not clog pores.

Overview:

This formula contains no oil, no lanolin, and no fragrances. It is powerful yet gentle, and one a beauty award for the best moisturizer for oily skin. It has soothing aloe vera and antioxidants such as grape seed extract to help fight free radicals and radical oxygen species.(6)

It also contains vitamins A (as retinyl palmitate), B5, B3 (niacinamide), vitamin C (magnesium ascorbyl phosphate), and vitamin E (tocopheryl acetate) to help combat wrinkles and fine lines for a younger appearance.(7)

Squalene and sodium hyaluronate help to boost moisture for a supple appearance.(8) A dew formation occurs due to humidity in the environment and surface temperature. As a humectant, it is termed a moisturizing dew as a scientifically formulated moisturizer.

This comfortable hydrator also provides an anti-aging formula.

Main ingredients:

Water, glycerin, squalene, beeswax, grape seed extract, aloe, vitamins A, C, E, B5, B3.

The good:

  • Absorbs quickly to hydrate skin
  • Oil-free, ultra-light moisturizer
  • Restores water levels
  • Strengthens moisture

Things to think about:

  • Since it is ultra-light, you may apply as often as needed. However, you may need to apply more often for greater hydration and a stronger, more aggressive level of moisturization

Bottom line:

It is an oil-, dye-, and fragrance-free moisturizer that is ultra-light without clogging pores. It may be applied as often as needed until the entire face is covered, and the skin feels hydrated.

3. ELEMIS S.O.S Emergency Cream Intensive Moisturizer

Best features:

  • Intensive daily moisturizer
  • Soothes dry, blemish-prone, and sensitive skin
  • Replenishes hydration balance in the skin

The best moisturizer to use with Differin for:

Those with sensitive, dry, parched, and weathered skin.

Overview:

This intensive daily moisturizer is formulated to soothe blemish-prone, dry, and sensitive skin while restoring its hydration balance. It is uniquely formulated with willow, myrrh essential oil, lavender absolute, and Centella asiatica as its main active ingredients.

It helps to protect the skin from environmental stressors while also replenishing moisture and providing balance.

Lavender is a commonly used essential oil with additional sedative properties. It has a sweet and balsamic fragrance, which helps to provide relaxation and calmness. It also helps to reduce pain, lessen the effects of injuries such as burns, and have anti-infectious properties.(9)

Myrrh essential oil has softening, regenerative, and purifying properties and has been used for its helpful effects for centuries.(5)

White willow bark is rich in salicylic acid and known for anti-inflammatory, skin calming, and soothing benefits.(10)

Main ingredients:

Lavender Absolute, Myrrh Essential Oil, white willow bark.

The good:

  • Intensive formula to soothe sensitive, dry and blemish-prone skin
  • Anti-inflammatory thanks to willow bark content
  • Replenishes the hydration balance of the skin

Things to think about:

  • Since it is an intensive moisturizer, it works very well for dry skin. However, it may feel too heavy for oily skin

Bottom line:

This intense, daily moisturizer is designed to soothe dry, sensitive, and blemish-prone skin while restoring the skin’s hydration balance, leaving the skin soothed, comforted, and replenished.

4. Murad Hydration Hydro-Dynamic Ultimate Moisture

Best features:

  • Luxurious, lightweight face cream
  • Advanced hyaluronic acid technology
  • 24-hour hydration
  • Reduces fine lines and wrinkles
  • Restores suppleness

The best moisturizer to use with Differin for:

Those looking to restore youthfulness and plumpness.

Overview:

The Murad hydration hydro-dynamic ultimate moisture cream provides hydration in the formula of a luxurious yet lightweight cream.

Its main active ingredients include coconut extract, shea butter, hyaluronic acid and avocado, sunflower, and olive fruit oils. It provides relief to dehydrated and dry skin, while its hyaluronic acid formula helps to restore suppleness.

Hyaluronic acid helps to reduce the onset of fine lines and wrinkles, while coconut extract helps to retain moisture and give the skin a youthful and smooth texture.(11)

It can be mixed with makeup, foundation, or highlighters for a luminous glow. It can also be used with several skin types such as normal, dry, combination, or sensitive skin.

In addition, it is free of gluten, parabens, sulfates, animal-derived ingredients, and phthalates.

Main ingredients:

Hyaluronic acid, coconut extract, Shea Butter, Avocado, Sunflower, and Olive Fruit Oils.

The good:

  • Clinically proven to lock optimal moisture levels
  • Delivers instant comfort
  • Super-hydrating, moisture-rich formula
  • Anti-aging properties
  • Light and non-greasy

Things to think about:

  • It does not include sunscreen or sun protection, so its application will need to be followed by a sunscreen. While it is a hydrating moisturizer with anti-aging properties, it is not intended for use around the eyes

Bottom line:

This hydrating moisturizer contains an anti-aging formula that is light, non-greasy, and moisture-rich, as well as super hydrating. It locks in optimal moisture and delivers comfort. It can be applied liberally to the face, neck, and chest, avoiding the eyes and followed by a sunscreen. It helps to restore youthfulness, plumpness, and resilience to the skin.

5. Mario Badescu Aloe Moisturizer SPF 15

Best features:

  • Oil-free
  • Aloe-infused formula
  • Delivers lightweight, soothing hydration
  • Provides broad-spectrum, sun protection

The best moisturizer to use with Differin for:

Those looking for moderate sun protection.

Overview:

This moisturizer helps to protect oily, troubled skin while providing skin hydration. Its main active ingredient is aloe vera, which boosts the skin’s hydration.

It is formulated as a lightweight and oil-free moisturizer with aloe vera, water, glycerin, and stearic acid to replenish the skin, defend against harmful free radicals while avoiding a heavy feel.(12)

It can be applied daily throughout the face before sun exposure while avoiding the eyes. It is typically used after cleansing and toning. It should be re-applied after swimming, sweating, or exercising, as is recommended with most sunscreens to maintain the sun protection effect.

It can also be used as a stand-alone product or with makeup. If it gets into the eyes, it should be rinsed thoroughly with water.

Main ingredients: aloe vera, water, glycerin, stearic acid.

The good:

  • Daily sun protection
  • Sensitive skin formulation
  • Non-clogging hydration
  • Can be used under makeup

Things to think about:

  • It offers moderate sun protection at SPF 15, so stronger or additional forms of sun protection such as a greater SPF and a wide-brimmed hat may be advised when going into the sun or staying outdoors for extended periods of time

Bottom line:

This lightweight moisturizer can be used on a daily basis and also contains moderate sun protection. It is oil-free and aloe-based and provides hydration while not clogging pores. It can be used on sensitive skin and can be used underneath makeup.

6. ELEMIS Superfood Cica Calm Hydration Juice

Best features:

  • Hydrates, balances, and soothes skin
  • Vegan-friendly, silicone-free and paraben-free
  • Anti-oxidant-rich biotransformed Cica nourishes and calms the skin
  • Organic cucumber extract and aloe vera juice provides cooling hydration

The best moisturizer to use with Differin for:

Those looking for prebiotic formulas.

Overview:

This prebiotic gel helps to moisturize, leaving a cool, refreshed, and calm feel along with its biotransformed Cica.

It is 100% silicone-free, paraben-free, and vegan-friendly. Its formula is also rich in antioxidants with organic cucumber extract and aloe vera juice to provide a cooling, hydrating feel. Kiwi, green, and mandarin fruit waters help the skin look refreshed and bright, while antioxidants such as prebiotic Cica, organic aloe vera, and cucumber help to soothe and calm the skin.

Aloe vera has been used for centuries to calm and soothe the skin as a moisturizer and skin softener.(13) Bergamot is a popular essential oil with antibacterial and sedative properties.(14)

Cucumber is refreshing and soothing while regulating moisture and has been shown to help tighten the skin.(15) Orange essential oils have calming and soothing properties.(16) Sunflower seed oil is known to be a carrier oil with soothing properties.(17)

Coconut oil has many benefits, including its use as a soft emollient while leaving skin looking non-greasy. It melts when in contact with the skin and is solid at room temperature.(18) Spearmint soothes senses while also providing an aromatic experience and a pleasant scent.(19)

Glycerin is a well-known moisturizer that attracts and locks water into the skin while leaving it soft, supple, and hydrated.(12) Biotransformed Cica (Centenella asiatica) is also known as “tiger grass,” is rich in antioxidants, and helps dehydrated skin appear calm while reducing redness.(20)

Main ingredients:

Aloe vera, bergamot, cucumber, orange, sunflower seed oil, coconut, spearmint, glycerin, biotransformed Cica (Centenella asiatica).

The good:

  • Prebiotic formula
  • Gel moisturizer
  • Moisture-quenching
  • Contains soothing biotransformed Cica
  • Leaves complexion calm, cool, and refreshed

Things to think about:

  • The vehicle is a gel, which leads to a calm, cool, and refreshed feeling. Some individuals may prefer other vehicles that may feel different on the skin, such as emollients, lotions, or foams

Bottom line:

This moisture-quenching gel moisturizer contains prebiotics formulated with biotransformed Cica to hydrate the skin, leaving a cool, calm complexion that is refreshed. It can be used in upward strokes on the face, neck, and chest.

7. Jack Black Dry Erase Ultra-Calming Face Cream

Best features:

  • Calming facial cream
  • Delivers moisture to dry skin
  • Diminishes appearance of redness
  • Soothes facial skin

The best moisturizer to use with Differin for:

Those wanting to reduce redness.

Overview:

This calming cream soothes facial skin, delivers moisture to dry skin, and helps to reduce the appearance of redness.

Its ingredients have been tested clinically and contain botanical extracts and oils. It also serves as an ideal night treatment to use after exposure to environmental elements or to use after masks or peels.

It can be applied morning or evening for more intense hydration or can be used on clean skin at bedtime. It contains jojoba oil, aloe vera leaf juice, rice bran extract, ginger root, sweet almond oil, and tea tree fruit seeds as its main ingredients. Aloe vera leaf juice is rich in vitamins C and E and delivers antioxidant protection while soothing the skin.(13)

Jojoba oil helps to deliver superior hydration to deeply moisturize dry skin.(3) Rice bran extract is rich in moisturizing proteins, nourishing vitamins, and protective antioxidants.(21)

Ginger root blend helps to soothe the face and diminish redness.(22) Sweet almond oil and tea tree fruit seeds help provide immediate and sustained hydration to the skin.(23-24)

Main ingredients:

Aloe vera leaf juice, rice bran extract, jojoba oil, tea tree fruit seeds, sweet almond oil, ginger root blend.

The good:

  • Moisturizes dry skin
  • Reduces redness and soothes irritation
  • Ideal night treatment
  • Good to use after masks, peels, and elements

Things to think about:

  • The cream is best used at night but can be used twice a day – morning and evening – for a more intense hydrating effect

Bottom line:

This moisturizer delivers skin hydration to dry skin, reduces redness, and soothes irritated skin. It is ideally used at nighttime but can be used twice daily – also in the morning for a more intensive hydrating effect. It is also an ideal face cream to use after elements, peels, or masks.

8. L’Occitane Ultra-Rich Comforting Cream

Best features:

  • Ideal for dry to very dry skin
  • Provides nourishment
  • Contains shea butter for comfortable skin

The best moisturizer to use with Differin for:

Those with very dry skin.

Overview:

This ultra-rich, comforting cream contains a high concentration of shea butter (25%) to help meet the needs of dry to very dry skin, including sensitive skin.

The skin is moisturized for a lasting period of time (72 hours), leaving a soft, supple feeling while also reducing the tightness that can come with dryness. It can be used as a protector against external aggressors and used all day as it has been tested in different climates.

Shea butter is produced by hand in Burkina Faso, an African country. It has been found to leave the skin very soft while also containing omega 6 and karitene, which are molecules containing beneficial properties to provide nourishment and extra protection.

Organic shea butter is rich in fatty acids and is not saponifiable.(25)

It has been used for centuries in sub-Saharan Africa to protect and nourish the skin and hair as a beauty ingredient. It is sourced through traditional methods from Burkinabe women of Burkina Faso, who have developed a sustainable, fair trade and traditional supply chain for shea butter.

Main ingredients:

Shea butter

The good:

  • Infused with 25% shea butter
  • Melting texture
  • Ultra-rich comforting cream
  • Soothes dry to very dry skin
  • Locks in moisture all-day
  • Rich in vitamin E, omega 6

Things to think about:

  • Contains shea butter, which is ideal for dry to very dry skin, but may feel too strong or occlusive for oily or acne-prone skin

Bottom line:

This ultra-rich comforting cream helps to soothe very dry to dry skin by locking in moisture. It contains 25% shea butter, omega 6, and vitamin E, which help it meet the needs of those with very dry and sensitive skin. It’s specifically formulated to help protect and nourish the skin in need of intensive hydration.


Enjoying this article? Get similar skincare content direct to your inbox! Subscribe to our exclusive newsletter and we will help you master your routine. Receive regular tips and tricks, how-to's, special offers and more...

Enter your email below:

How we chose these products

Since Differin (or adapalene) is a commonly used topical retinoid that can serve different purposes from acne to anti-aging, it is essential that others know how to use them appropriately while keeping their skin looking healthy and intact.(1)

Differin can create a lot of irritation and peeling if not used properly with an effective moisturizer.(2)

The moisturizers used need to provide effective skin hydration and fulfill the role of a moisturizer. If they are not strong enough to hydrate the skin, they will not be good enough to battle the irritation that may be due to topical retinoids.

The moisturizers recommended need to also be useful and suitable for acne-prone skin, which is typically distinguished as “non-comedogenic.”

A comedone is the primary skin lesion in acne, and thus a moisturizer ideally should not lead to pimples or comedones, which are the primary skin lesions behind breakouts. The ideal moisturizer should actually compliment Differin by helping to control acne while also soothing, potentially irritated and dry skin.

Extensive research was carried out, taking into account experience, reviews, advantages, disadvantages, and ingredients to select the top 8 choices.

When checking ratings and reviews, what people said about the product mattered. The volume of reviews, as well as the pattern and emphasis on the comments, helps to give a reliable indication of which products people like the most due to their efficacy.

There is great variability in mind when selecting which options are best for which type of person, including different price points to meet different budgets, variety and range of ingredients, differences in textures such as lotion, gels, creams, emollients, occlusives, and humectants; sun protection factor (SPF) for daytime hydration and UV protection; gender differences taking into account female vs. male preferences; and different options which may suit different skin types.

The products that were chosen essentially needed a high concentration of key quality ingredients such as antioxidants, vitamins, natural or organic ingredients, and also be of benefit to the skin, including in cases of sensitive skin, acne-prone skin, dry skin, and skin irritation.

Thus, through extensive research and investigation, taking into account many of these factors, the top 8 choices were selected, which would most likely be suitable for your skin and boost your self-confidence.

Frequently asked questions

What if my skin continues to breakout with the moisturizer while using Differin?

If your skin continues to breakout while using Differin and a moisturizer, it is best to re-evaluate your skincare routine and acne regimen with your dermatologist.

We all go through phases with our skin, and acne is definitely a skin condition with many ups and downs. It is essential to periodically re-evaluate your skincare regimen to make sure it is what suits you and works best for your skin at that moment in time.

Acne can also change dramatically depending on age, stressors, food, pregnancy status, and past medical and family history, as well as medications and other external influences.

When should I use a moisturizer with SPF?

You should always wear sunscreen and SPF 30 or above whenever you plan on going outdoors. I personally apply mine after waking up in the morning and before leaving the house to avoid unwanted sun exposure.

In the evening, SPF is not necessary as there is no sunlight. A good moisturizer without SPF will do for soothing the skin right before bedtime.

What kinds of moisturizers should I look for with acne-prone skin?

Just because you have acne-prone skin does not mean you do not need a moisturizer. I have oily skin and use a moisturizer on a daily basis, morning and evening. What to look for when choosing a moisturizer for acne-prone or oily skin is one that is preferably oil-free and also non-comedogenic, which means it won’t leave an oily residue or clog pores.

How should I apply a moisturizer?

A moisturizer is best applied after washing the face and right before bedtime. After washing your face, your skin is damp – this is when the skin best locks in moisture.

Your skin and the rest of your body tend to regenerate and heal at bedtime while resting. If you are experiencing any irritation, sensitivity, or rashes from Differin or any other treatments or skin conditions, it is essential to apply skin hydrating products right before bedtime to allow the skin to heal and improve.

Conclusion

Although Differin is a commonly used product ranging from adolescents to adults, which can be used for a variety of conditions – most notably acne, hyperpigmentation, and anti-aging, it can still be irritating and drying, causing peeling in the skin, which may make someone never choose to use it again.

Using a moisturizer in conjunction with using Differin is not only recommended but almost essential to fare well with treatment. Which moisturizer to use is also up to your goals, budget, skin type, and personal experience.

If you are building a skincare regimen to use with Differin for yourself, begin by using a moisturizer that doesn’t just prevent irritation, flaking, and dryness, but also leaves your skin packed with good ingredients and antioxidants to leave it looking healthy, supple, glowing and intact.

What is your favorite moisturizer to use that is both oil-free and non-comedogenic?

And on that note, which moisturizer do you find best works when using Differin to prevent breakouts while still soothing your skin?

We are looking forward to hearing your views and experiences.

Did you find this article useful? Enter your email to receive subscriber-only skincare advice to help you perfect your routine and achieve radiant skin. Get tips and tricks, how to's and exclusive offers direct to your inbox...

Enter your email below:


References

1. Tolaymat L, Zito PM. Adapalene. [Updated 2020 May 14]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK482509/

2. Piskin S, Uzunali E. A review of the use of adapalene for the treatment of acne vulgaris. Ther Clin Risk Manag. 2007;3(4):621-624.

3. Pazyar N, Yaghoobi R, Ghassemi MR, Kazerouni A, Rafeie E, Jamshydian N. Jojoba in dermatology: a succinct review. G Ital Dermatol Venereol. 2013;148(6):687-691.

4. Dawid-Pać R. Medicinal plants used in treatment of inflammatory skin diseases. Postepy Dermatol Alergol. 2013;30(3):170-177. doi:10.5114/pdia.2013.35620

5. Orchard A, van Vuuren S. Commercial Essential Oils as Potential Antimicrobials to Treat Skin Diseases. Evid Based Complement Alternat Med. 2017;2017:4517971. doi:10.1155/2017/4517971

6. Soleymani S, Iranpanah A, Najafi F, et al. Implications of grape extract and its nanoformulated bioactive agent resveratrol against skin disorders. Arch Dermatol Res. 2019;311(8):577-588. doi:10.1007/s00403-019-01930-z

7. Menni S, Piccinno R. La vitamina A e la vitamina E in dermatologia [Vitamin A and vitamin E in dermatology]. Acta Vitaminol Enzymol. 1985;7 Suppl:55-60.

8. Huang ZR, Lin YK, Fang JY. Biological and pharmacological activities of squalene and related compounds: potential uses in cosmetic dermatology. Molecules. 2009;14(1):540-554. Published 2009 Jan 23. doi:10.3390/molecules14010540

9. Białoń M, Krzyśko-Łupicka T, Nowakowska-Bogdan E, Wieczorek PP. Chemical Composition of Two Different Lavender Essential Oils and Their Effect on Facial Skin Microbiota. Molecules. 2019;24(18):3270. Published 2019 Sep 8. doi:10.3390/molecules24183270

10. Gopaul R, Knaggs HE, Lephart JF, Holley KC, Gibson EM. An evaluation of the effect of a topical product containing salicin on the visible signs of human skin aging. J Cosmet Dermatol. 2010;9(3):196-201. doi:10.1111/j.1473-2165.2010.00512.x

11. Bukhari SNA, Roswandi NL, Waqas M, et al. Hyaluronic acid, a promising skin rejuvenating biomedicine: A review of recent updates and pre-clinical and clinical investigations on cosmetic and nutricosmetic effects. Int J Biol Macromol. 2018;120(Pt B):1682-1695. doi:10.1016/j.ijbiomac.2018.09.188

12. Milani M, Sparavigna A. The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study. Clin Cosmet Investig Dermatol. 2017;10:311-315. Published 2017 Aug 11. doi:10.2147/CCID.S144180

13. Feily A, Namazi MR. Aloe vera in dermatology: a brief review. G Ital Dermatol Venereol. 2009;144(1):85-91.

14. Perna S, Spadaccini D, Botteri L, et al. Efficacy of bergamot: From anti-inflammatory and anti-oxidative mechanisms to clinical applications as preventive agent for cardiovascular morbidity, skin diseases, and mood alterations. Food Sci Nutr. 2019;7(2):369-384. Published 2019 Jan 25. doi:10.1002/fsn3.903

15. Kapoor S, Saraf S. Assessment of viscoelasticity and hydration effect of herbal moisturizers using bioengineering techniques. Pharmacogn Mag. 2010;6(24):298-304. doi:10.4103/0973-1296.71797

16. Dawid-Pać R. Medicinal plants used in treatment of inflammatory skin diseases. Postepy Dermatol Alergol. 2013;30(3):170-177. doi:10.5114/pdia.2013.35620

17. Danby SG, AlEnezi T, Sultan A, et al. Effect of olive and sunflower seed oil on the adult skin barrier: implications for neonatal skin care. Pediatr Dermatol. 2013;30(1):42-50. doi:10.1111/j.1525-1470.2012.01865.x

18. Kim S, Jang JE, Kim J, et al. Enhanced barrier functions and anti-inflammatory effect of cultured coconut extract on human skin. Food Chem Toxicol. 2017;106(Pt A):367-375. doi:10.1016/j.fct.2017.05.060

19. Grant P, Ramasamy S. An update on plant derived anti-androgens. Int J Endocrinol Metab. 2012;10(2):497-502. doi:10.5812/ijem.3644

20. Bylka W, Znajdek-Awiżeń P, Studzińska-Sroka E, Dańczak-Pazdrowska A, Brzezińska M. Centella asiatica in dermatology: an overview. Phytother Res. 2014;28(8):1117-1124. doi:10.1002/ptr.5110

21. Su Jeong Ha, Joon Park, Jangho Lee, Kyung-Mo Song, Min Young Um, Suengmok Cho & Sung Keun Jung (2018) Rice bran supplement prevents UVB-induced skin photoaging in vivo, Bioscience, Biotechnology, and Biochemistry, 82:2, 320-328, DOI: 10.1080/09168451.2017.1417021

22. Bode AM, Dong Z. The Amazing and Mighty Ginger. In: Benzie IFF, Wachtel-Galor S, eds. Herbal Medicine: Biomolecular and Clinical Aspects. 2nd ed. Boca Raton (FL): CRC Press/Taylor & Francis; 2011.

23. Ahmad Z. The uses and properties of almond oil. Complement Ther Clin Pract. 2010;16(1):10-12. doi:10.1016/j.ctcp.2009.06.015

24. Pazyar N, Yaghoobi R, Bagherani N, Kazerouni A. A review of applications of tea tree oil in dermatology. Int J Dermatol. 2013;52(7):784-790. doi:10.1111/j.1365-4632.2012.05654.x

25. Hon KL, Tsang YC, Pong NH, et al. Patient acceptability, efficacy, and skin biophysiology of a cream and cleanser containing lipid complex with shea butter extract versus a ceramide product for eczema. Hong Kong Med J. 2015;21(5):417-25. doi: 10.12809/hkmj144472.

About The Author

Dr. Anna Chacon MD FAAD
Dr. Anna Chacon MD FAAD

Dr. Anna Chacon is a board-certified dermatologist from Miami, based in South Florida. She graduated from Brown University’s highly selective Program in Liberal Medical Education. She completed her dermatology residency at the University of Southern California, where she learned firsthand about skin disorders that others only read about. She loves to write, see patients, and practice all aspects of dermatology.

Leave a Reply

Your email address will not be published. Required fields are marked *

FREE shipping above $40 in US, Canada, UK, & Europe. Above $75, internationally. 30-day WORRY-FREE returns.